Vaping or Cigarettes: What's Better for You? Vaping vs Smoking: Key Differences Explained Vape Direct Heated Tobacco Products, Cigarettes, and E Cigarettes: What's the Difference PMI Science Vaping vs. Smoking Infographic VapeMountain.com Toki Let's be real, what's the difference between vaping versus smoking cigarettes? We know that vaping contains no tobacco and far less chemicals than cigarettes but the keyword here is 'less'.